Isatis Root is a traditional herb for clearing Heat and detoxification, cooling Blood, reducing swelling in the throat. Modern research has proved its antibacterial, anti-viral, anti-endotoxin, anti-inflammatory, and enhancing immune function. Therefore, it is widely used to prevent and treat bacterial and viral infections like acute tonsillitis and mumps, and chronic viral infections.

Since the nature of Isatis Root is cold, people with a weak constitution should use it with Qi nourishing herbs. For example, for the prevention of influenza, it can be combined with Tonic Defensive Qi; for the prevention of viral hepatitis, it can be combined with Shaoyang Formula. To treat the Chronic Fatigue Syndrome/Myalgic encephalomyelitis it is used with Shaoyang Formula.